Mission Statement: The mission of the Somatic Cancer Workgroup is to facilitate the development of data curation guidelines and standards to determine the clinical actionability of somatic alterations in cancer, thereby enhancing the usability, dissemination and implementation of cancer somatic changes in the ClinGen resource & other knowledgebases including CIViC, ClinVar, and the GA4GH VICC-metaKB.
Vision Statement: The Somatic Cancer Workgroup aims to collaborate with expert groups to develop processes that support accurate determination of the clinical significance of somatic changes for use by physicians, clinical laboratories, researchers, and guideline-developing groups, to improve patient care through genomic medicine.
The CIViC Knowledge Model and Standard Operating Procedures for Curation and Clinical Interpretation of Variants in CancerCuration Activity Procedures - July 14, 2019
Integrating somatic variant data and biomarkers for germline variant classification in cancer predisposition genesPublications - October 11, 2018
Somatic cancer variant curation and harmonization through consensus minimum variant level dataPublications - November 1, 2016
Working Group Membership
Membership spans many fields, including genetics, medical, academia, and industry.