Hereditary Hearing Loss Variant Curation Expert Panel

The ClinGen Hearing Loss Expert Panel represents members at over 15 institutions across 4 continents, with a diverse array of backgrounds, including physicians (clinical geneticists, otolaryngologists, neuro-otologists,), clinical laboratory diagnosticians, and clinical and basic research scientists and genetic counselors. All members have a focus on the genetics and genomics of hearing loss. 

The Hearing Loss Expert Panel aims to specify the existing ACMG guidelines for variant classification in hearing loss genes and review variants for expert classification including resolving discrepancies in existing variant classification in ClinVar prioritizing the most common genes and variants associated to hearing loss.

Expert Status - In progress

Step 1
Step 2
Step 3
Step 4
Define Group
Develop Classification Rules
Pilot Rules
In progress
Expert Panel Approval


Ahmad Abou Tayoun, PhD

Sami Amr, PhD

Heidi Rehm, PhD


Please contact a coordinator if you have questions.

Andrea Oza, MS, CGC


Membership in this committee spans many fields, including genetics, medical, academia, and industry. [View Members]
For more information, please contact:

Andrea Oza, MS, CGC


A systematic process of evaluating evidence to classify a genomic variant on a spectrum from pathogenic to benign with respect to a particular disease and inheritance pattern.