Clinical Domain Working Groups

Hereditary Cancer CDWG

Expert Panels Documents Membership

The Hereditary Cancer Working Group aims to centralize and curate genetic knowledge in order to develop guidance for molecular diagnostic germline cancer testing.


  1. Identify laboratories that are generating data in the clinical domain to facilitate data submission to ClinVar
  2. Serve as the liaison between locus specific databases and similar research efforts to create partnerships with ClinVar Expert Panel status
  3. Implement the ClinGen Gene Curation Working Group's Clinical Validity classifications and prioritize curation of genes on hereditary cancer panels
  4. Establish robust variant curation rules and processes for hereditary cancer genes

Expert Panels


Please contact a coordinator if you have questions.


CDWG Membership

Membership spans many fields, including genetics, medical, academia, and industry.