Clinical Domain Working Groups

Cardiovascular CDWG

Expert Panels Documents Membership

The Cardiovascular Disease Working Group aims to create a comprehensive, standardized knowledge base of genes and variants relevant for cardiovascular genetic and genomic medicine. 

Goals:

  1. Identify clinical cardiovascular molecular genetic laboratories and facilitate their data submission to ClinVar.
  2. Identify and recruit domain experts who are willing and able to participate in projects including but not limited to gene and variant curation.
  3. Develop and implement variant curation processes for cardiovascular disease genes.
  4. Disseminate expert consensus gene and variant curations via ClinVar and publications.
  5. Curate and adjudicate genes associated with cardiovascular disease using the ClinGen Gene Curation Working Group gene:disease classification framework.
  6. Define the phenotypic and other data that are needed to assess pathogenicity (e.g., functional assays, histopathology).

Expert Panels

Chairs

Coordinators
Please contact a coordinator if you have questions.