ClinGen's Curation Interfaces

Currently, only the Variant Pathogenicity Curation Interface is open to the public. The other interfaces are available to ClinGen biocurators and expert panel members only.  
Results of all curation activities are available to the public through our Search feature.

Additional Curation Resources

Evidence Repository

Expert curated interpretations for variants' pathogenicity.

Allele Registry

Provides unique allele identifiers 

ClinGen Curated Genes & Diseases

List of genes and diseases curated by ClinGen 

Microarray Tracks

Tools for microarray analysis including custom tracks and array design files 

Pathogenicity Calculator

Enter ACMG-AMP evidence tags to generate classifications

Structural Variation Database Search

Search our database of thousands of structural variation cases 

ClinVar Miner

Tool for exploring ClinVar data at different levels of granularity 

Dosage Sensitivity Curations

Evidence supporting or refuting the dosage sensitivity of individual genes and genomic regions

Resources for Laboratories & Clinicians

ClinGen Search

Search ClinGen's curated resources

Consent Resources

Consent template for broad data sharing

How to Share Your Data

Resources to share data with ClinVar and GenomeConnect

External Genomics Resources

Search genomics resources outside of ClinGen

Get Involved

Ways to participate in ClinGen activities

Clinical Lab Data Sharing List

View list of clinical labs who meet a minimum standard of data sharing 

Variant Interpretation Discrepancy Resolution Module

A module towards Part IV Practive Improvement for clinical laboratory geneticists. 

GenomeConnect: The ClinGen Patient Registry


Sign up or log in to GenomeConnect

GenomeConnect Consent

Read the GenomeConnect consent form 

GenomeConnect Body System Survey

Preview the GenomeConnect health survey

Other GenomeConnect Resources

FAQs, recruitment materials and more

Registry Data Sharing List

View a list of patient registries that meet minimum standards of data sharing

How to Share Patient Data

Resources for patients and patient groups to share data with ClinVar