Dosage Sensitivity Curation

The ClinGen Dosage Sensitivity curation process collects evidence supporting/refuting the haploinsufficiency and triplosensitivity of genes and genomic regions.

Educational and Training Materials

Powerpoint slides, videos, handouts, etc. for those interested in curating dosage sensitivity using the ClinGen method.

Learn More
Dosage Sensitivity Curation Interface

Currently available for ClinGen Biocurators. Log-in required.

Learn More
Dosage Sensitivity Results

Search by genes or genomic coordinates, or download the entire dosage sensitivity dataset.

Learn More
Documents & Announcements

Documents and announcements related to Gene-Disease Clinical Validity Curation.

Learn More