ClinGen is defining the clinical relevance of genes and variants

ClinGen was founded in 2013 by the National Human Genome Research Institute, ClinGen is a growing collaborative effort, involving three grants, nine principal investigators and over 1,100 contributors from more than 30 countries. Below are a series of recent updates that ClinGen has been working on.

ACMG/ClinGen Technical Standards for CNVs

Our in-depth, multi-part overview of the new ACMG/ClinGen technical standards for interpretation and reporting of constiutional CNVs has concluded. All recordings are available.

PAR-20-101 Genomic Expert Curation Panel Opportunity

FOA to establish Expert Panels which will use ClinGen and NCBI's ClinVar procedures and infrastructure.

Volunteer to Curate

Please take a brief survey to tell us more about your interests and desired level of involvement so we can pair you with an appropriate curation activity and/or Expert Panel.

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Curation Activities